HEALTHONLINEUS

### Fast and Simple Instant Pot Spaghetti with Meat Sauce Recipe

#### Introduction
Instant Pot spaghetti with meat sauce is a flavorful and easy meal that can be made in a fraction of the time required for traditional cooking. This recipe merges the deep tastes of a robust meat sauce with perfectly cooked spaghetti, all in a single pot. Perfect for hectic weeknights or a warm family gathering, this dish is bound to delight everyone around the table.

#### Ingredients
– 1 pound ground beef or Italian sausage
– 1 medium onion, chopped
– 3 cloves garlic, minced
– 1 can (28 ounces) crushed tomatoes
– 2 cups beef broth or water
– 1 teaspoon dried oregano
– 1 teaspoon dried basil
– 1 teaspoon salt
– ½ teaspoon black pepper
– 1 pound spaghetti (uncooked)
– 1 tablespoon olive oil
– Grated Parmesan cheese (for serving)
– Fresh basil or parsley (for garnish, optional)

#### Instructions

1. **Sauté the Meat and Vegetables**
– Set the Instant Pot to “Sauté” mode. Pour in olive oil and allow it to heat.
– Add the chopped onion and sauté for about 2-3 minutes until it becomes translucent.
– Add minced garlic and cook for another 30 seconds until aromatic.
– Incorporate the ground beef or Italian sausage, breaking it apart with a spatula. Cook until it’s browned, roughly 5-7 minutes. Drain excess fat if needed.

2. **Add the Sauce Ingredients**
– Mix in the crushed tomatoes, beef broth (or water), oregano, basil, salt, and pepper. Stir well to combine.

3. **Add the Spaghetti**
– Snap the spaghetti in half and gently place it into the sauce mixture. Do not stir; simply ensure the pasta is mostly submerged in the liquid.

4. **Pressure Cook**
– Secure the lid of the Instant Pot and set the valve to “Sealing.” Choose the “Manual” or “Pressure Cook” option and set the timer for 8 minutes.
– After the cooking time ends, let the pressure release naturally for 5 minutes, then carefully switch the valve to “Venting” to release any remaining pressure.

5. **Serve**
– Remove the lid and mix the spaghetti and sauce together until well blended. If the sauce seems too thick, you can add a bit more broth or water to achieve your preferred consistency.
– Serve hot, garnished with grated Parmesan cheese and fresh herbs if desired.

#### Tips
– For an extra kick, consider adding red pepper flakes to the sauce.
– Ground turkey or chicken can be used as a leaner alternative.
– Add veggies like bell peppers or mushrooms for additional nutrition.

#### Conclusion
This fast and simple Instant Pot spaghetti with meat sauce recipe is a lifesaver for busy cooks. With minimal preparation and cleanup, you can savor a warm and fulfilling meal in no time. Ideal for families or meal prepping, this dish is sure to become a favorite in your weeknight dinner lineup. Enjoy!

On International Clinical Trials Day, the UK’s MHRA unveiled a major shift: a consultation on using external control arms (ECAs) based on real-world data (RWD) for regulatory decisions. This move aims to leverage patient-level data collected outside clinical studies to compare the efficacy and safety of interventions in clinical trials. Stakeholders have until the end […]

The post External Control Arms Based on Real World Data: MHRA Consultation Opens appeared first on Healthcare & Life Sciences Blog.

Brussels has finally blinked. On 8 September 2025, the European Commission launched a call for evidence to simplify the MDR and IVDR. The window is short — it closes on 6 October 2025, but the signal is clear: the Commission is ready to revisit rules that have become heavier than the risk they were meant […]

The post Medical Devices and In Vitro Diagnostic Regulations: Brussels Signals It’s Ready to Cut Red Tape? appeared first on Healthcare & Life Sciences Blog.

### Fast Instant Pot Pozole Rojo Recipe

Pozole Rojo is a classic Mexican soup that features hominy, meat (typically pork or chicken), and a flavorful red chili broth. This warm dish is commonly topped with fresh ingredients such as cabbage, radishes, lime, and avocado. Utilizing an Instant Pot greatly shortens the cooking time, making it convenient for a weeknight meal. Here’s a quick and straightforward recipe for Instant Pot Pozole Rojo.

#### Ingredients

– **For the Pozole:**
– 2 lbs pork shoulder, diced into 1-inch chunks
– 1 can (15 oz) hominy, drained and rinsed
– 4 cups chicken or pork broth
– 1 medium onion, diced
– 4 cloves garlic, minced
– 2-3 dried guajillo chiles, stems and seeds removed
– 1-2 dried ancho chiles, stems and seeds removed
– 1 tsp cumin
– 1 tsp oregano
– Salt and pepper to taste
– 2 tbsp vegetable oil

– **For Garnishing:**
– Shredded cabbage
– Sliced radishes
– Chopped cilantro
– Lime wedges
– Avocado slices
– Crumbled queso fresco (optional)

#### Instructions

1. **Prepare the Chiles:**
– In a small saucepan, bring 2 cups of water to a boil. Add the guajillo and ancho chiles and let them soak for about 15 minutes until they are softened. Drain and set aside.

2. **Blend the Sauce:**
– In a blender, combine the soaked chiles, garlic, cumin, oregano, and 1 cup of broth. Blend until smooth. Set aside.

3. **Sauté the Pork:**
– Set the Instant Pot to the sauté mode. Add vegetable oil and allow it to heat. Add the diced onion and sauté for approximately 3-4 minutes until translucent.
– Introduce the pork pieces and brown on all sides, about 5-7 minutes.

4. **Add Ingredients:**
– Pour the blended chili sauce over the browned pork. Add the remaining broth and hominy. Stir to mix well.

5. **Pressure Cook:**
– Close the Instant Pot lid and make sure the valve is set to sealing. Select the manual or pressure cook function and set the timer for 30 minutes on high pressure.

6. **Release Pressure:**
– After the cooking time concludes, allow for a natural release for 10 minutes, then cautiously switch the valve to venting to release any remaining pressure.

7. **Serve:**
– Taste the pozole and modify the seasoning with salt and pepper as necessary. Spoon the pozole into bowls and serve hot with garnishes on the side.

#### Tips

– For a spicier pozole, add extra chiles or incorporate a jalapeño into the blend.
– If you prefer chicken, swap the pork shoulder for boneless, skinless chicken thighs and shorten the cooking time to 20 minutes.
– This dish can be prepared in advance and kept in the refrigerator for up to 3 days. The flavors will intensify as it sits.

#### Conclusion

This Fast Instant Pot Pozole Rojo recipe provides a delightful and filling meal that captures the essence of traditional Mexican cuisine in a fraction of the time. With its rich flavors and customizable toppings, it’s ideal for family gatherings or a cozy evening at home. Savor your homemade pozole with your favorite garnishes for a truly fulfilling experience!

Amid fluctuating tariffs and complex trade policies, healthcare and life sciences (HLS) companies face mounting operational and legal challenges within their global supply chains. Organizations are taking steps to retool their supply chains in response to threats against stability, but change introduces myriad knock-on implications.   In the second article of the series, we explore four key […]

The post Healthcare & Life Sciences Supply Chains Series: Trade Winds, Tariffs, and Optimizing Operations (2 of 4) appeared first on Healthcare & Life Sciences Blog.

### Wholesome Creamy Chicken Corn Chowder Made Without Heavy Cream

#### Introduction
Corn chowder is a delightful dish that typically showcases a rich, creamy foundation. Nonetheless, classic recipes may contain high calories and fat owing to the inclusion of heavy cream. This piece introduces a healthier take on creamy chicken corn chowder that preserves the dish’s comforting nature while incorporating lighter components.

#### Ingredients
– 1 pound boneless, skinless chicken breasts, chopped
– 1 tablespoon olive oil
– 1 medium onion, chopped
– 2 cloves garlic, minced
– 3 cups fresh or frozen corn kernels
– 2 medium potatoes, peeled and chopped
– 4 cups low-sodium chicken broth
– 1 cup unsweetened almond milk (or any plant-based milk)
– 1 teaspoon dried thyme
– 1 teaspoon smoked paprika
– Salt and pepper to taste
– Fresh parsley or chives for garnish

#### Instructions

1. **Sauté the Chicken**: In a large saucepan, warm the olive oil over medium heat. Add the chopped chicken breasts and season with salt and pepper. Cook until the chicken is browned and fully cooked, about 5-7 minutes. Remove the chicken from the pot and set aside.

2. **Cook the Vegetables**: In the same saucepan, incorporate the chopped onion and minced garlic. Sauté for about 3-4 minutes until the onion turns translucent.

3. **Add Corn and Potatoes**: Mix in the corn kernels and chopped potatoes. Cook for another 2-3 minutes, allowing the flavors to come together.

4. **Combine with Broth**: Pour in the chicken broth and bring the mix to a boil. Lower the heat to a simmer and cook until the potatoes are soft, around 15 minutes.

5. **Blend for Creaminess**: After the potatoes are tender, use an immersion blender to puree a portion of the chowder right in the pot. This will yield a creamy consistency without using heavy cream. If you like a chunkier chowder, blend only half of the mixture.

6. **Add Chicken and Milk**: Return the cooked chicken to the pot and incorporate the almond milk, dried thyme, and smoked paprika. Simmer for another 5 minutes to heat it through. Adjust seasoning with salt and pepper if necessary.

7. **Serve**: Spoon the chowder into bowls and garnish with fresh parsley or chives. Savor your wholesome creamy chicken corn chowder!

#### Nutritional Benefits
This chowder is loaded with nutrients:
– **Lean Protein**: Chicken breast offers a significant source of lean protein, vital for muscle recovery and overall wellness.
– **Vitamins and Minerals**: Corn and potatoes provide an abundance of vitamins A and C, potassium, and fiber, supporting digestive health.
– **Lower in Calories**: By substituting almond milk for heavy cream, this recipe markedly cuts calories and fat while still achieving a creamy texture.

#### Conclusion
This wholesome creamy chicken corn chowder is an excellent substitute for conventional recipes that depend on heavy cream. With its nourishing ingredients and comforting tastes, it’s ideal for a cozy meal at any time of the year. Relish this guilt-free version that fulfills your cravings without sacrificing your health!

### Parmesan-Crusted Zucchini Recipe

Parmesan-crusted zucchini is a delightful and nutritious side dish that enhances the inherent flavors of zucchini while featuring a crispy, cheesy layer. This recipe is easy to make and can be savored as an appetizer, side, or even a light snack. Here’s how to prepare it.

#### Ingredients

– 2 medium zucchinis
– 1 cup grated Parmesan cheese
– 1 cup breadcrumbs (panko is recommended for additional crunch)
– 1 teaspoon garlic powder
– 1 teaspoon onion powder
– 1 teaspoon dried Italian herbs (like oregano or basil)
– Salt and pepper to taste
– 2 large eggs
– Olive oil spray or cooking spray

#### Instructions

1. **Preheat the Oven**: Set your oven to 425°F (220°C). Line a baking sheet with parchment paper or lightly coat it with cooking spray.

2. **Prepare the Zucchini**: Rinse the zucchinis and trim the ends. Cut them into ½-inch thick rounds or sticks, based on your preference.

3. **Set Up the Breading Station**: In one bowl, beat the eggs. In another bowl, mix the grated Parmesan cheese, breadcrumbs, garlic powder, onion powder, Italian herbs, salt, and pepper.

4. **Coat the Zucchini**: Dip each piece of zucchini into the beaten eggs, letting any excess drip off. Next, coat it in the Parmesan-breadcrumb mixture, ensuring it’s fully covered. Arrange the coated zucchini on the prepared baking sheet.

5. **Spray with Olive Oil**: Lightly mist the coated zucchini with olive oil spray. This will assist in achieving a golden, crispy finish while baking.

6. **Bake**: Position the baking sheet in the preheated oven and bake for about 20-25 minutes, or until the zucchini is tender and the coating is golden brown and crispy. Turn the zucchini halfway through baking for uniform crispness.

7. **Serve**: Take them out of the oven and allow to cool slightly. Serve warm as a side dish or appetizer. They pair excellently with marinara sauce or a yogurt-based dip.

#### Tips

– For extra flavor, consider blending in some grated lemon zest or crushed red pepper flakes into the breadcrumb mixture.
– If you seek a gluten-free alternative, swap regular breadcrumbs for gluten-free breadcrumbs or almond flour.
– Try different cheeses, like cheddar or mozzarella, for a unique variation.

#### Nutritional Benefits

Zucchini is low in calories and rich in vitamins A and C, making it a healthy addition to your meals. The Parmesan cheese contributes protein and calcium, while the breadcrumbs offer fiber. This dish is a fantastic way to include more vegetables in your diet without compromising taste.

Savor this Parmesan-crusted zucchini recipe as a delicious and nutritious substitute for classic fried snacks!

The German Accessibility Strengthening Act (BFSG), implementing the European Accessibility Act Directive (EU 2019/882), takes effect on June 28, 2025. While medical devices themselves are not within the scope as a product category, accessibility requirements may still apply where medical device software operates on EAA-covered hardware (e.g., smartphones, tablets). E-commerce services, including webshops selling medical […]

The post Germany’s implementation of the European Accessibility Act (EAA) – Are medical devices affected? appeared first on Healthcare & Life Sciences Blog.

AI as a medical device (AIaMD) in Europe is at a crossroads. As manufacturers grapple with compliance under two separate legal regimes – the EU AI Act (AIA) and EU Medical Device Regulations (MDR) – concerns are mounting around the sluggish pace of Notified Body designations and glaring inconsistencies between the two frameworks. Can the […]

The post The EU AI Act and Medical Devices: Innovation or Insanity Ahead?  appeared first on Healthcare & Life Sciences Blog.

**Traditional Niçoise Salad: A Culinary Delight from the French Riviera**

The Niçoise salad, or “Salade Niçoise,” is a vibrant and flavorful dish that hails from the sunny city of Nice on the French Riviera. This classic salad is a celebration of fresh, Mediterranean ingredients and is renowned for its harmonious blend of flavors and textures. It is a staple in French cuisine and has gained popularity worldwide for its simplicity and deliciousness.

**Ingredients and Composition**

A traditional Niçoise salad is composed of a variety of fresh ingredients that reflect the region’s rich culinary heritage. The key components typically include:

1. **Tuna**: Traditionally, the salad features oil-packed tuna, which adds a rich, savory flavor. Some variations use fresh seared tuna for a more modern twist.

2. **Olives**: Niçoise olives, small and briny, are essential to the salad, providing a distinct Mediterranean taste. They are often pitted and scattered throughout the dish.

3. **Vegetables**: The salad is abundant with fresh vegetables such as ripe tomatoes, crisp green beans, and tender new potatoes. These ingredients are usually cooked al dente to retain their texture and flavor.

4. **Eggs**: Hard-boiled eggs are sliced and added to the salad, offering a creamy contrast to the other components.

5. **Anchovies**: While not always included, anchovies are a traditional ingredient that adds a salty depth to the salad.

6. **Capers**: These small, pickled flower buds enhance the salad with their tangy, piquant flavor.

7. **Lettuce**: A bed of fresh lettuce, often Bibb or Boston, serves as the base for the salad, providing a crisp and refreshing element.

8. **Dressing**: A classic vinaigrette made with olive oil, red wine vinegar, Dijon mustard, garlic, and herbs like thyme or basil ties the salad together with its zesty and aromatic profile.

**Preparation and Presentation**

The beauty of a Niçoise salad lies in its artful arrangement. Each ingredient is carefully prepared and placed to create a visually appealing and appetizing dish. The vegetables are typically blanched to maintain their vibrant color and crispness. The salad is often served as a composed dish, with each ingredient grouped separately on a large platter or individual plates, allowing diners to appreciate the variety of flavors and textures.

**Cultural Significance**

The Niçoise salad is more than just a dish; it is a representation of the Mediterranean lifestyle and the emphasis on fresh, seasonal produce. It embodies the essence of Provençal cuisine, which is characterized by its reliance on local ingredients and simple preparation methods that highlight natural flavors.

**Variations and Modern Interpretations**

While the traditional Niçoise salad adheres to specific ingredients, modern interpretations have introduced variations to suit different tastes and dietary preferences. Some versions incorporate grilled or canned tuna, while others experiment with different types of olives or add bell peppers for extra color and sweetness. Vegetarian versions might omit the tuna and anchovies, substituting them with chickpeas or artichoke hearts.

**Conclusion**

The traditional Niçoise salad is a timeless dish that continues to captivate food enthusiasts with its delightful combination of flavors and textures. Whether enjoyed as a light lunch, a starter, or a main course, it offers a taste of the Mediterranean and a glimpse into the culinary traditions of the French Riviera. Its enduring popularity is a testament to the universal appeal of fresh, high-quality ingredients prepared with care and simplicity.