Month: September 2024

The European Parliament could have helped to stimulate R&D into new drugs for rare diseases if it had not stuck so closely to the European Commission’s original proposals on orphan exclusivity periods, we argue in this piece for the Pink Sheet (paywall). This article is a continuation from our previous analysis on the Commission’s proposals […]

The post Has the European Parliament Missed the Chance to Boost Orphan Drug Development? appeared first on Healthcare & Life Sciences Blog.

**Title: The Culinary Delight of Large Lemon-Infused Gigante Beans**

**Introduction**

Gigante beans, also known as “giant beans” or “fasolia gigantes” in Greek, are a staple in Mediterranean cuisine, particularly in Greece. These large, creamy beans are known for their rich texture and ability to absorb flavors, making them a versatile ingredient in a variety of dishes. One of the most delightful ways to prepare these beans is by infusing them with lemon, creating a dish that is both refreshing and satisfying. In this article, we’ll explore the origins of Gigante beans, their nutritional benefits, and how to prepare a delicious lemon-infused Gigante bean dish that will elevate your culinary repertoire.

**Origins and Cultural Significance**

Gigante beans are native to the Mediterranean region, where they have been cultivated for centuries. They are a type of runner bean (Phaseolus coccineus) and are particularly popular in Greek cuisine. In Greece, Gigante beans are often used in traditional dishes such as “Gigantes Plaki,” a baked bean dish with tomatoes, onions, and herbs. The beans are celebrated for their ability to absorb the flavors of the ingredients they are cooked with, making them a beloved ingredient in many Mediterranean households.

**Nutritional Benefits**

Gigante beans are not only delicious but also packed with nutritional benefits. They are an excellent source of plant-based protein, making them a great option for vegetarians and vegans. Additionally, they are rich in dietary fiber, which promotes digestive health and helps regulate blood sugar levels. Gigante beans are also a good source of essential vitamins and minerals, including iron, magnesium, and folate. The combination of protein, fiber, and nutrients makes these beans a powerhouse of nutrition that can support overall health and well-being.

**The Magic of Lemon Infusion**

Lemon is a key ingredient in Mediterranean cuisine, known for its ability to brighten and enhance the flavors of a dish. When combined with Gigante beans, lemon adds a refreshing tang that complements the creamy texture of the beans. The acidity of the lemon helps to balance the richness of the beans, creating a harmonious flavor profile that is both light and satisfying. Lemon-infused Gigante beans can be served as a side dish, a main course, or even as part of a mezze platter.

**How to Prepare Large Lemon-Infused Gigante Beans**

**Ingredients:**
– 1 cup dried Gigante beans (or 2 cups cooked)
– 1/4 cup extra virgin olive oil
– 1 large lemon (zested and juiced)
– 2 cloves garlic, minced
– 1 small onion, finely chopped
– 1 teaspoon dried oregano (or fresh oregano, chopped)
– 1/2 teaspoon ground cumin (optional)
– Salt and pepper to taste
– Fresh parsley, chopped (for garnish)

**Instructions:**

1. **Soak the Beans:** If using dried Gigante beans, start by soaking them in water overnight or for at least 8 hours. This will help soften the beans and reduce cooking time. After soaking, drain and rinse the beans.

2. **Cook the Beans:** Place the soaked beans in a large pot and cover them with fresh water. Bring to a boil, then reduce the heat and simmer for about 1 to 1.5 hours, or until the beans are tender. If using pre-cooked beans, skip this step.

3. **Prepare the Lemon Infusion:** While the beans are cooking, heat the olive oil in a large skillet over medium heat. Add the chopped onion and sauté until translucent, about 5 minutes. Add the minced garlic and cook for another 1-2 minutes, until fragrant.

4. **Add the Beans:** Once the beans are cooked, drain them and add them to the skillet with the onions and garlic. Stir to combine.

5. **Infuse with Lemon:** Add the lemon zest, lemon juice, oregano, and cumin (if using) to the skillet. Stir well to ensure the beans are evenly coated with the lemon and herb mixture. Season with salt and pepper to taste.

6. **Simmer:** Reduce the heat to low and let the beans simmer in the lemon mixture for about 10-15 minutes, allowing the flavors to meld together.

7. **Serve:** Transfer the lemon-infused Gigante beans to a serving dish and garnish with freshly chopped parsley. Serve warm or at room temperature.

**Serving Suggestions**

Lemon-infused Gigante beans can be enjoyed in a variety of ways. They make a wonderful side dish for grilled meats or fish, adding a bright and zesty contrast to richer flavors. They can also be served as a main course, accompanied by a simple green salad and crusty bread. For a more casual meal, consider serving the beans as part of a mezze platter, alongside other Mediterranean favorites like hummus, tzatziki, and

The conversation on psychedelics around the world continues to evolve, with more and more emerging clinical data highlighting their potential to treat mental health disorders. Last year’s developments – see our previous blog post here – led us to anticipate an upcoming change but yet the legal landscape remains unchanged. In the UK, the independent […]

The post Psychedelics – will reform happen fast enough? appeared first on Healthcare & Life Sciences Blog.

**Homemade Mixed Berry Pie Recipe: A Delightful Treat for All Seasons**

Few desserts can rival the comforting allure of a homemade pie, and when it comes to flavor, a Mixed Berry Pie is a true showstopper. Bursting with the vibrant flavors of fresh berries and encased in a buttery, flaky crust, this pie is a celebration of the best that nature has to offer. Whether you’re a seasoned baker or a novice in the kitchen, this recipe will guide you through the steps to create a delicious Mixed Berry Pie that’s sure to impress your family and friends.

### Ingredients

**For the Pie Crust:**
– 2 ½ cups all-purpose flour
– 1 tablespoon granulated sugar
– 1 teaspoon salt
– 1 cup (2 sticks) unsalted butter, chilled and cubed
– 6-8 tablespoons ice water

**For the Berry Filling:**
– 4 cups mixed berries (such as strawberries, blueberries, raspberries, and blackberries)
– ¾ cup granulated sugar (adjust to taste)
– ¼ cup cornstarch
– 1 tablespoon lemon juice
– 1 teaspoon lemon zest
– 1 teaspoon vanilla extract
– 1 tablespoon unsalted butter, cut into small pieces

**For the Egg Wash:**
– 1 egg, beaten
– 1 tablespoon milk or water

**Optional:**
– Coarse sugar for sprinkling on top

### Instructions

#### Step 1: Prepare the Pie Crust

1. **Mix Dry Ingredients:** In a large mixing bowl, whisk together the flour, sugar, and salt.

2. **Cut in the Butter:** Add the chilled, cubed butter to the flour mixture. Using a pastry cutter or your fingertips, work the butter into the flour until the mixture resembles coarse crumbs with some pea-sized pieces of butter remaining.

3. **Add Ice Water:** Gradually add the ice water, one tablespoon at a time, mixing gently with a fork or your hands until the dough just comes together. Be careful not to overwork the dough.

4. **Form the Dough:** Divide the dough into two equal portions. Shape each portion into a disk, wrap in plastic wrap, and refrigerate for at least 1 hour (or up to 2 days). This allows the gluten to relax and the butter to firm up, resulting in a tender, flaky crust.

#### Step 2: Prepare the Berry Filling

1. **Combine the Berries:** In a large bowl, gently toss the mixed berries with the sugar, cornstarch, lemon juice, lemon zest, and vanilla extract. Ensure the berries are evenly coated. Let the mixture sit for about 10 minutes to allow the flavors to meld and the cornstarch to begin thickening the juices.

#### Step 3: Assemble the Pie

1. **Preheat the Oven:** Preheat your oven to 400°F (200°C).

2. **Roll Out the Dough:** On a lightly floured surface, roll out one disk of dough to fit a 9-inch pie dish, leaving a slight overhang. Carefully transfer the rolled dough to the pie dish, pressing it gently into the bottom and sides.

3. **Add the Filling:** Pour the berry mixture into the prepared pie crust, spreading it out evenly. Dot the filling with small pieces of butter.

4. **Top the Pie:** Roll out the second disk of dough and place it over the filling. You can either cover the pie completely or create a lattice pattern by cutting the dough into strips and weaving them over the filling. Trim any excess dough and crimp the edges to seal.

5. **Egg Wash:** Brush the top crust with the beaten egg wash and sprinkle with coarse sugar for added sweetness and crunch.

#### Step 4: Bake the Pie

1. **Bake:** Place the pie on a baking sheet to catch any drips and bake in the preheated oven for 20 minutes. Then, reduce the oven temperature to 375°F (190°C) and continue baking for an additional 30-35 minutes, or until the crust is golden brown and the filling is bubbling.

2. **Cool:** Once baked, remove the pie from the oven and let it cool on a wire rack for at least 2 hours. This allows the filling to set, making it easier to slice.

### Serving Suggestions

Serve your homemade Mixed Berry Pie warm or at room temperature with a scoop of vanilla ice cream or a dollop of whipped cream. The contrast of the warm, juicy berries with the cold, creamy ice cream is simply divine.

### Tips for Success

– **Use Fresh or Frozen Berries:** Fresh berries are ideal, but if they’re out of season, frozen berries work just as well. If using frozen berries, do not thaw them before mixing with the other ingredients.
– **Adjust Sweetness:** Depending on the natural sweetness of

In 2021, the U.S. Food and Drug Administration (FDA), Health Canada, and the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) collaboratively identified ten guiding principles for good machine learning practice (GMLP). These principles aim to ensure the safe, effective, and high-quality development of AI/ML technologies in medical devices. Building on GMLP, these agencies are […]

The post Machine Learning Medical Devices – FDA, UK MHRA and Health Canada Join Forces (Again) in Promoting Transparency appeared first on Healthcare & Life Sciences Blog.

**Creamy Zucchini Soup Recipe: A Delicious and Nutritious Comfort Food**

As the weather cools down and the days grow shorter, there’s nothing quite as comforting as a warm bowl of soup. If you’re looking for a dish that’s both delicious and nutritious, creamy zucchini soup is an excellent choice. This versatile recipe is easy to make, packed with vitamins and minerals, and can be adapted to suit a variety of dietary preferences. Whether you’re a seasoned chef or a kitchen novice, this creamy zucchini soup is sure to become a staple in your culinary repertoire.

### Why Zucchini?

Zucchini, also known as courgette, is a summer squash that is low in calories but high in essential nutrients. It’s an excellent source of vitamins A and C, potassium, and dietary fiber. Zucchini is also rich in antioxidants, which help protect your cells from damage caused by free radicals. Its mild flavor makes it a versatile ingredient that can be used in a variety of dishes, from salads to stir-fries to baked goods. In this recipe, zucchini takes center stage, creating a creamy, velvety soup that’s both satisfying and healthy.

### Ingredients

To make a basic creamy zucchini soup, you’ll need the following ingredients:

– **2 tablespoons of olive oil or butter**: For sautéing the vegetables and adding richness to the soup.
– **1 medium onion, chopped**: Adds depth of flavor and sweetness to the soup.
– **2 cloves of garlic, minced**: Provides a subtle, aromatic kick.
– **4 medium zucchinis, chopped**: The star of the dish, providing the bulk of the soup.
– **4 cups of vegetable or chicken broth**: The base of the soup, adding flavor and helping to create a smooth consistency.
– **1 medium potato, peeled and chopped**: Adds creaminess and body to the soup without the need for heavy cream.
– **1/2 cup of heavy cream or coconut milk**: For an extra layer of creaminess (optional).
– **Salt and pepper to taste**: Essential for seasoning the soup.
– **Fresh herbs (such as basil, thyme, or parsley)**: For garnish and added flavor.

### Optional Add-Ins

– **Parmesan cheese**: A sprinkle of grated Parmesan can add a savory, umami flavor to the soup.
– **Croutons**: For added texture and crunch.
– **Lemon zest or juice**: To brighten the flavors and add a touch of acidity.

### Instructions

1. **Prepare the Vegetables**: Begin by washing and chopping the zucchini, onion, and potato. Mince the garlic.

2. **Sauté the Aromatics**: In a large pot, heat the olive oil or butter over medium heat. Add the chopped onion and sauté until it becomes translucent, about 5 minutes. Add the minced garlic and cook for an additional 1-2 minutes, being careful not to let it burn.

3. **Cook the Vegetables**: Add the chopped zucchini and potato to the pot. Stir to combine with the onions and garlic. Cook for about 5 minutes, allowing the vegetables to soften slightly.

4. **Add the Broth**: Pour in the vegetable or chicken broth, making sure the vegetables are fully submerged. Bring the mixture to a boil, then reduce the heat to low and let it simmer for 15-20 minutes, or until the zucchini and potato are tender.

5. **Blend the Soup**: Once the vegetables are cooked through, remove the pot from the heat. Use an immersion blender to puree the soup until it reaches a smooth, creamy consistency. If you don’t have an immersion blender, you can carefully transfer the soup to a blender in batches and blend until smooth. Be sure to let the soup cool slightly before blending to avoid any accidents.

6. **Add Creaminess**: If you’re using heavy cream or coconut milk, stir it into the soup at this stage. This will add a luxurious texture and richness to the dish. Season the soup with salt and pepper to taste.

7. **Serve and Garnish**: Ladle the creamy zucchini soup into bowls and garnish with fresh herbs, a drizzle of olive oil, or a sprinkle of Parmesan cheese. Serve with crusty bread or croutons for a complete meal.

### Variations

– **Vegan Version**: To make the soup vegan, use vegetable broth and substitute the heavy cream with coconut milk or a plant-based cream alternative.
– **Spicy Kick**: Add a pinch of red pepper flakes or a dash of hot sauce for a spicy twist.
– **Herb-Infused**: Experiment with different herbs, such as dill, cilantro, or chives, to create unique flavor profiles.

### Nutritional Benefits

This creamy zucchini soup is not only delicious but also packed with nutrients. Zucchini is low in calories and high in water

Hungary has taken over the EU Council’s rotating presidency as of 1 July 2024. Hungary’s EU presidency comes at a time when the European Parliament (EP) has already adopted its position on the EU pharma reform, and the file is now in the Council’s hands. In this article, we review Hungary’s EU presidency program and […]

The post What to Expect From Hungary’s EU Presidency? appeared first on Healthcare & Life Sciences Blog.

**Healthy and Satisfying Lunch Ideas for a Boost in Mood**

In the hustle and bustle of daily life, lunch often becomes an afterthought—a quick bite grabbed between meetings or a hastily assembled sandwich eaten at your desk. However, the food we consume at midday plays a crucial role in sustaining our energy levels, improving our mood, and enhancing our overall well-being. A well-balanced lunch can be the difference between a sluggish afternoon and a productive, positive one. Here are some healthy and satisfying lunch ideas that not only nourish your body but also give your mood a much-needed boost.

### 1. **Mediterranean Quinoa Salad**

The Mediterranean diet is renowned for its heart-healthy benefits and its ability to improve mental health. A Mediterranean quinoa salad combines the best of this diet with the protein-packed goodness of quinoa.

**Ingredients:**
– Quinoa (cooked)
– Cherry tomatoes
– Cucumbers
– Red onions
– Kalamata olives
– Feta cheese
– Chickpeas
– Extra virgin olive oil
– Lemon juice
– Fresh herbs (parsley, basil)

**Why It Boosts Mood:**
Quinoa is a complete protein, meaning it contains all nine essential amino acids, which are crucial for brain function. The olive oil and fatty fish (like salmon, if you choose to add it) are rich in omega-3 fatty acids, which have been shown to reduce symptoms of depression. The vibrant colors and fresh flavors of the salad can also be visually and sensorially uplifting.

### 2. **Avocado and Turkey Wrap**

Wraps are a convenient and versatile lunch option. An avocado and turkey wrap is not only delicious but also packed with nutrients that support brain health.

**Ingredients:**
– Whole grain or spinach wrap
– Sliced turkey breast (preferably organic and nitrate-free)
– Avocado slices
– Baby spinach
– Tomato slices
– Hummus or Greek yogurt spread
– A sprinkle of flaxseeds or chia seeds

**Why It Boosts Mood:**
Avocados are rich in healthy fats, particularly monounsaturated fats, which support brain health and cognitive function. They also contain folate, which is essential for the production of serotonin, a neurotransmitter that regulates mood. Turkey is a good source of tryptophan, an amino acid that the body uses to produce serotonin. The whole grains in the wrap provide a steady release of energy, helping to prevent the afternoon slump.

### 3. **Lentil and Vegetable Soup**

A warm bowl of lentil and vegetable soup is comforting and nourishing, perfect for colder days or when you need a mood boost.

**Ingredients:**
– Lentils (red or green)
– Carrots
– Celery
– Onions
– Garlic
– Spinach or kale
– Tomatoes
– Vegetable broth
– Spices (turmeric, cumin, black pepper)

**Why It Boosts Mood:**
Lentils are a great source of plant-based protein and fiber, which help stabilize blood sugar levels and keep you feeling full and satisfied. They also contain iron, which is essential for energy production and can help combat fatigue. The vegetables provide a variety of vitamins and minerals, while the spices like turmeric have anti-inflammatory properties that may help reduce symptoms of depression.

### 4. **Salmon and Sweet Potato Bowl**

This lunch option is both filling and packed with nutrients that support mental health.

**Ingredients:**
– Grilled or baked salmon
– Roasted sweet potatoes
– Steamed broccoli or asparagus
– Brown rice or quinoa
– A drizzle of tahini or lemon-dill sauce

**Why It Boosts Mood:**
Salmon is one of the best sources of omega-3 fatty acids, which are crucial for brain health and have been linked to a lower risk of depression. Sweet potatoes are rich in complex carbohydrates, which help maintain stable blood sugar levels and provide a steady source of energy. They are also high in vitamin B6, which is important for the production of neurotransmitters like serotonin. The combination of protein, healthy fats, and complex carbs in this bowl will keep you satisfied and energized throughout the afternoon.

### 5. **Chickpea and Spinach Stuffed Pita**

For a quick and easy lunch, a chickpea and spinach stuffed pita is a great option. It’s packed with fiber, protein, and a variety of vitamins and minerals.

**Ingredients:**
– Whole grain pita bread
– Chickpeas (cooked or canned)
– Fresh spinach
– Red bell peppers
– Cucumber slices
– Tzatziki sauce or hummus
– A sprinkle of sunflower seeds

**Why It Boosts Mood:**
Chickpeas are high in fiber and protein, which help keep you full and satisfied. They also contain magnesium, which plays a role in mood regulation. Spinach is rich in folate, which is essential

Alongside its allies, the EU has implemented a vast volume of sanctions on Russia and Belarus following Russia’s invasion of Ukraine in February 2022.  The EU sanctions against both Russia and Belarus are at the core of the EU’s response to Russia’s military aggression and aim to diminish Russian resources and curb Russia’s capacity to […]

The post Further EU Sanctions Tighten on Russia and Belarus – Impacting the Healthcare Sector appeared first on Healthcare & Life Sciences Blog.

**How to Make Light and Fluffy Pancakes: A Step-by-Step Guide**

There’s nothing quite like waking up to the smell of freshly made pancakes. Whether you’re preparing breakfast for your family or treating yourself to a weekend brunch, light and fluffy pancakes are the ultimate comfort food. But achieving that perfect texture can sometimes be tricky. Fear not! With the right ingredients, techniques, and a little bit of patience, you can create pancakes that are airy, tender, and absolutely delicious. Here’s how:

### 1. **Start with the Right Ingredients**
The foundation of any great pancake lies in the ingredients. Here’s what you’ll need:

– **Flour:** All-purpose flour is the most commonly used, but you can also experiment with whole wheat or gluten-free flours.
– **Baking Powder:** This is the leavening agent that helps your pancakes rise and become fluffy.
– **Sugar:** A small amount of sugar adds sweetness and helps with browning.
– **Salt:** Just a pinch to balance the flavors.
– **Eggs:** Eggs provide structure and richness to the batter.
– **Milk:** Milk adds moisture and helps create a smooth batter. You can use whole milk, buttermilk, or even a non-dairy alternative.
– **Butter:** Melted butter adds flavor and richness to the pancakes.
– **Vanilla Extract (optional):** A splash of vanilla adds a lovely aroma and flavor.

### 2. **Measure Your Ingredients Accurately**
Baking is a science, and accurate measurements are key to achieving the perfect pancake texture. Use measuring cups and spoons to ensure you’re using the right amounts of each ingredient. Too much flour can make your pancakes dense, while too much liquid can make them flat and soggy.

### 3. **Mix the Dry Ingredients**
In a large mixing bowl, whisk together the flour, baking powder, sugar, and salt. Whisking helps to evenly distribute the ingredients and aerate the flour, which contributes to a lighter pancake.

### 4. **Mix the Wet Ingredients Separately**
In a separate bowl, whisk together the eggs, milk, melted butter, and vanilla extract (if using). Make sure the butter is slightly cooled before adding it to the eggs to prevent curdling.

### 5. **Combine the Wet and Dry Ingredients**
Pour the wet ingredients into the dry ingredients. Gently fold the mixture together using a spatula or wooden spoon. Be careful not to overmix the batter—this is crucial for achieving fluffy pancakes. Overmixing can develop the gluten in the flour, resulting in tough and chewy pancakes. It’s okay if the batter is slightly lumpy; these lumps will disappear as the pancakes cook.

### 6. **Let the Batter Rest**
Allowing the batter to rest for about 5-10 minutes before cooking gives the baking powder time to activate and the gluten to relax. This step helps create a lighter, fluffier texture.

### 7. **Preheat the Griddle or Pan**
Preheat a non-stick griddle or skillet over medium heat. You’ll know it’s ready when a few drops of water sizzle and evaporate upon contact. Lightly grease the surface with butter or oil, but be careful not to use too much, as excess grease can cause uneven browning.

### 8. **Cook the Pancakes**
Using a ladle or measuring cup, pour about ¼ cup of batter onto the griddle for each pancake. Cook until bubbles form on the surface and the edges start to look set, about 2-3 minutes. Flip the pancake with a spatula and cook for another 1-2 minutes on the other side until golden brown. Avoid pressing down on the pancakes with the spatula, as this can deflate them and make them less fluffy.

### 9. **Keep Pancakes Warm**
If you’re making a large batch, keep the cooked pancakes warm by placing them on a baking sheet in a 200°F (93°C) oven. This will keep them warm without drying them out.

### 10. **Serve and Enjoy**
Serve your light and fluffy pancakes with your favorite toppings. Classic choices include butter and maple syrup, but you can also get creative with fresh fruit, whipped cream, nuts, or even a drizzle of chocolate sauce.

### **Bonus Tips for Perfect Pancakes:**

– **Use Buttermilk:** For an extra tangy flavor and even fluffier texture, substitute regular milk with buttermilk. The acidity in buttermilk reacts with the baking powder to create more air bubbles in the batter.
– **Don’t Overcrowd the Pan:** Cook only a few pancakes at a time to ensure even cooking and easy flipping.
– **Adjust the Heat:** If your pancakes are browning too quickly, reduce the heat slightly. If they’re taking too long to cook, increase the heat a bit.