HEALTHONLINEUS

**Researchers at ISS National Lab Investigate Age-Related Muscle Loss in Microgravity Environment**

As human space exploration advances, one of the most pressing challenges facing astronauts is the impact of long-term space travel on the human body. Among the many physiological changes that occur in space, muscle atrophy, or the loss of muscle mass and strength, is a significant concern. This phenomenon is exacerbated by the microgravity environment of space, which reduces the need for muscles to support body weight and perform daily activities. To better understand this process and its implications for both astronauts and aging populations on Earth, researchers at the International Space Station (ISS) National Lab are conducting groundbreaking studies on age-related muscle loss in microgravity.

### The Problem of Muscle Atrophy in Space

Muscle atrophy is a well-documented issue for astronauts who spend extended periods in space. In the absence of Earth’s gravitational pull, muscles, particularly those in the legs, back, and core, are not required to work as hard to maintain posture or perform movements. As a result, astronauts can lose up to 20% of their muscle mass in just a few weeks of spaceflight. This loss of muscle strength and endurance can have serious consequences, especially during long-duration missions to the Moon, Mars, or beyond, where physical performance is critical for survival and mission success.

On Earth, muscle atrophy is also a significant concern for aging populations. As people age, they naturally experience a decline in muscle mass and strength, a condition known as sarcopenia. Sarcopenia can lead to decreased mobility, increased risk of falls, and a reduced quality of life. Understanding the mechanisms behind muscle loss in space could provide valuable insights into the aging process on Earth and lead to the development of new treatments for sarcopenia.

### Microgravity as a Model for Aging

The microgravity environment aboard the ISS provides a unique opportunity to study muscle atrophy in a controlled setting. In space, muscle loss occurs at an accelerated rate compared to aging on Earth, allowing researchers to observe changes in muscle tissue over a shorter period. By studying how muscles respond to microgravity, scientists can gain a better understanding of the molecular and cellular processes that contribute to muscle atrophy.

One of the key advantages of conducting research on the ISS is the ability to isolate the effects of microgravity from other factors that contribute to muscle loss, such as physical inactivity or poor nutrition. This allows researchers to focus specifically on how the absence of gravity affects muscle tissue at the molecular level, including changes in gene expression, protein synthesis, and muscle fiber composition.

### Key Research Initiatives

Several research initiatives are currently underway at the ISS National Lab to investigate age-related muscle loss in microgravity. These studies involve a combination of human and animal models, as well as advanced technologies such as tissue engineering and molecular biology techniques.

1. **Rodent Research Studies**: Rodents are frequently used as model organisms for studying muscle atrophy in space. These animals experience similar muscle loss to humans in microgravity, making them ideal subjects for investigating the underlying mechanisms of muscle atrophy. Researchers can analyze muscle tissue samples from rodents to identify changes in gene expression, protein levels, and cellular structures that occur in response to microgravity. These findings can then be applied to human muscle biology.

2. **Tissue Chips in Space**: Tissue chips, or organ-on-a-chip technology, are miniature models of human organs that can be used to study the effects of microgravity on specific tissues, including muscle. These chips are made from human cells and can mimic the structure and function of muscle tissue. By sending tissue chips to the ISS, researchers can observe how muscle cells respond to microgravity at the cellular and molecular levels. This technology allows for more precise experiments and could lead to the development of new therapies for muscle loss.

3. **Exercise Countermeasures**: Exercise is one of the most effective ways to combat muscle atrophy in space. Astronauts aboard the ISS follow a rigorous exercise regimen that includes resistance training and cardiovascular workouts to maintain muscle mass and strength. However, researchers are constantly exploring new exercise protocols and equipment that could be more effective in preventing muscle loss. Studies on the ISS are helping to refine these countermeasures and improve their efficacy for long-duration space missions.

4. **Pharmacological Interventions**: In addition to exercise, researchers are investigating potential pharmacological treatments for muscle atrophy. Some studies focus on identifying drugs that can mimic the effects of exercise or stimulate muscle growth in microgravity. These treatments could be beneficial not only for astronauts but also for individuals on Earth who are unable to engage in regular physical activity due to illness, injury, or aging.

### Implications for Space Exploration and Earth

The findings from these studies have far-reaching implications for both space exploration and healthcare on Earth. For space missions, understanding how to prevent or mitigate muscle atrophy is essential for ensuring the health and performance of astronauts during long-duration missions. As

# Arbital Health and Quartet Health Collaborate to Enhance Value-Based Mental Healthcare

In recent years, the healthcare industry has seen a significant shift toward value-based care, a model that emphasizes patient outcomes and quality of care over the volume of services provided. This shift is particularly important in the realm of mental healthcare, where traditional fee-for-service models often fail to address the complexities of mental health conditions. In a groundbreaking move to further this transition, **Arbital Health** and **Quartet Health** have announced a strategic collaboration aimed at enhancing value-based mental healthcare services.

## The Need for Value-Based Mental Healthcare

Mental health disorders, including anxiety, depression, and substance use disorders, affect millions of people worldwide. According to the World Health Organization (WHO), depression is the leading cause of disability globally, while the National Institute of Mental Health (NIMH) estimates that nearly one in five adults in the U.S. lives with a mental illness. Despite the prevalence of mental health conditions, access to quality care remains a significant challenge, with many patients either not receiving the care they need or receiving care that is fragmented and ineffective.

Traditional fee-for-service models in mental healthcare often incentivize providers based on the quantity of services delivered rather than the quality or outcomes of those services. This can lead to inefficiencies, misaligned incentives, and suboptimal patient care. In contrast, value-based care models focus on improving patient outcomes, enhancing care coordination, and reducing unnecessary costs. These models are particularly well-suited to mental healthcare, where long-term, holistic approaches are often necessary to achieve meaningful improvements in patient well-being.

## Arbital Health: A Leader in Value-Based Care

Arbital Health is a leading healthcare organization that specializes in value-based care models. The company has a strong track record of working with healthcare providers, payers, and technology partners to implement innovative care delivery models that prioritize patient outcomes. Arbital Health’s approach is centered on data-driven decision-making, care coordination, and the integration of behavioral health services into primary care settings.

By focusing on value-based care, Arbital Health aims to improve the quality of care for patients while reducing overall healthcare costs. The company has developed a range of tools and resources to help providers transition to value-based care models, including population health management platforms, care coordination tools, and performance analytics.

## Quartet Health: Bridging the Gap Between Mental and Physical Health

Quartet Health is a technology-driven mental healthcare company that seeks to bridge the gap between mental and physical health. The company’s platform connects primary care providers, mental health specialists, and patients to ensure that individuals receive the right care at the right time. Quartet Health’s technology enables providers to identify patients with unmet mental health needs, facilitate referrals to appropriate mental health specialists, and track patient progress over time.

One of Quartet Health’s key strengths is its ability to integrate mental healthcare into primary care settings. This is particularly important because many individuals with mental health conditions first seek care from their primary care providers. By facilitating collaboration between primary care providers and mental health specialists, Quartet Health helps ensure that patients receive comprehensive, coordinated care.

## The Collaboration: A New Era of Value-Based Mental Healthcare

The collaboration between Arbital Health and Quartet Health represents a significant step forward in the evolution of value-based mental healthcare. By combining Arbital Health’s expertise in value-based care models with Quartet Health’s technology platform and focus on mental health integration, the two companies aim to create a more efficient, patient-centered approach to mental healthcare delivery.

### Key Objectives of the Collaboration

1. **Improved Care Coordination**: One of the primary goals of the collaboration is to enhance care coordination between primary care providers and mental health specialists. By leveraging Quartet Health’s platform, Arbital Health will be able to facilitate seamless referrals and communication between providers, ensuring that patients receive timely and appropriate care.

2. **Data-Driven Decision Making**: Both companies are committed to using data to drive improvements in care delivery. Arbital Health’s population health management tools, combined with Quartet Health’s patient tracking and analytics capabilities, will enable providers to monitor patient outcomes, identify gaps in care, and make informed decisions about treatment plans.

3. **Integration of Behavioral Health into Primary Care**: The collaboration will focus on integrating behavioral health services into primary care settings, a key component of value-based mental healthcare. By embedding mental health services within primary care practices, the partnership aims to reduce the stigma associated with seeking mental health treatment and improve access to care.

4. **Patient-Centered Care**: At the heart of the collaboration is a commitment to delivering patient-centered care. Both Arbital Health and Quartet Health recognize that mental health conditions are complex and require personalized, holistic approaches. The partnership will prioritize patient engagement, shared decision-making, and the use of evidence-based treatment protocols to improve patient outcomes.

5. **Cost Reduction**: Value-based care models are designed to reduce unnecessary healthcare costs by focusing on prevention, early intervention, and coordinated

**Google Partners with India and Thailand to License AI Model for Diabetic Retinopathy Detection**

In a significant stride toward leveraging artificial intelligence (AI) for healthcare, Google has announced partnerships with India and Thailand to license its AI model for detecting diabetic retinopathy (DR), a leading cause of blindness among adults worldwide. This collaboration marks a crucial step in addressing the growing burden of diabetes-related eye diseases in regions where healthcare resources are often stretched thin.

### The Growing Challenge of Diabetic Retinopathy

Diabetic retinopathy is a complication of diabetes that affects the eyes. It occurs when high blood sugar levels damage the blood vessels in the retina, the light-sensitive tissue at the back of the eye. If left untreated, it can lead to vision impairment and even blindness. According to the World Health Organization (WHO), diabetic retinopathy is responsible for 2.6% of global blindness, and the numbers are rising as diabetes becomes more prevalent.

India and Thailand are among the countries with the highest diabetes rates globally. India alone is home to over 77 million people with diabetes, and the numbers are projected to rise to 134 million by 2045. Thailand, too, faces a growing diabetes epidemic, with an estimated 4.8 million people living with the condition. In both countries, diabetic retinopathy screening programs are often limited by a lack of trained specialists and infrastructure, particularly in rural areas. This is where AI can play a transformative role.

### Google’s AI Model for Diabetic Retinopathy Detection

Google has been working on AI-driven healthcare solutions for several years, and one of its most promising developments is an AI model that can detect diabetic retinopathy from retinal images. The model uses deep learning techniques to analyze retinal photographs and identify signs of the disease with a high degree of accuracy. In clinical studies, the AI system has demonstrated performance comparable to that of human ophthalmologists in detecting both mild and severe cases of diabetic retinopathy.

The AI model works by analyzing retinal images captured by fundus cameras, which are commonly used in eye exams. It can detect early signs of diabetic retinopathy, such as microaneurysms, hemorrhages, and abnormal blood vessel growth, allowing for timely intervention and treatment. Early detection is critical because diabetic retinopathy can be managed effectively if caught in its early stages, reducing the risk of vision loss.

### The Partnership with India and Thailand

Google’s decision to license its AI model to India and Thailand is a strategic move aimed at addressing the healthcare challenges posed by diabetic retinopathy in these countries. The partnerships will involve collaboration with local healthcare providers, government agencies, and research institutions to integrate the AI model into existing screening programs.

In India, Google has partnered with the Aravind Eye Care System, one of the largest eye care providers in the world, and Sankara Nethralaya, a leading eye hospital. These institutions will use Google’s AI model to enhance their diabetic retinopathy screening programs, particularly in rural and underserved areas where access to specialized care is limited. The AI system will help streamline the screening process, allowing healthcare workers to identify patients who need further evaluation by an ophthalmologist.

In Thailand, Google has partnered with the Rajavithi Hospital in Bangkok, one of the country’s largest public hospitals. The AI model will be integrated into Thailand’s national diabetic retinopathy screening program, which aims to provide regular eye exams to people with diabetes. By automating the initial screening process, the AI system will help reduce the workload on healthcare providers and ensure that more patients receive timely diagnoses.

### The Role of AI in Expanding Access to Healthcare

One of the most significant advantages of using AI for diabetic retinopathy detection is its potential to expand access to healthcare in regions with limited resources. In many parts of India and Thailand, there is a shortage of trained ophthalmologists and eye care specialists, making it difficult to provide regular screenings to all people with diabetes. AI can help bridge this gap by enabling non-specialist healthcare workers to perform initial screenings using retinal images.

The AI model can also help reduce the time and cost associated with diabetic retinopathy screening. Traditional screening methods require a trained specialist to manually examine retinal images, which can be time-consuming and expensive. By automating this process, the AI system can quickly identify patients who need further evaluation, allowing healthcare providers to focus their resources on those who are most at risk.

### Ethical Considerations and Challenges

While the use of AI in healthcare holds great promise, it also raises important ethical considerations. One concern is the potential for bias in AI algorithms, which could lead to disparities in healthcare outcomes. Google has emphasized that its AI model has been trained on diverse datasets to ensure that it performs well across different populations. However, ongoing monitoring and evaluation will be necessary to ensure that the system continues to deliver accurate and equitable results.

Another challenge is the integration of AI into existing healthcare systems. In both India and

**Indonesia Approves Taiwanese AI Technology for Osteoporosis Screening: A Leap Forward in Healthcare Innovation**

In a significant development for both healthcare and technological innovation, Indonesia has recently approved the use of Taiwanese artificial intelligence (AI) technology for osteoporosis screening. This decision marks a pivotal moment in the country’s efforts to enhance its medical diagnostic capabilities, particularly in the early detection and management of osteoporosis, a condition that affects millions of people globally.

### The Growing Burden of Osteoporosis

Osteoporosis is a chronic condition characterized by the weakening of bones, making them more susceptible to fractures. It is often referred to as a “silent disease” because it progresses without symptoms until a fracture occurs. According to the International Osteoporosis Foundation (IOF), osteoporosis affects approximately 200 million people worldwide, with a significant proportion of cases occurring in Asia. In Indonesia, the aging population and lifestyle factors have contributed to a growing prevalence of osteoporosis, making early detection and intervention crucial.

Traditionally, osteoporosis is diagnosed using bone mineral density (BMD) tests, such as dual-energy X-ray absorptiometry (DEXA) scans. However, access to such diagnostic tools is often limited in developing countries due to high costs, lack of infrastructure, and a shortage of trained healthcare professionals. This has created a pressing need for more accessible, cost-effective, and accurate screening methods.

### The Role of AI in Healthcare

Artificial intelligence has emerged as a transformative force in healthcare, offering new ways to enhance diagnostic accuracy, streamline workflows, and improve patient outcomes. AI algorithms can analyze vast amounts of medical data, identify patterns, and provide insights that may not be immediately apparent to human clinicians. In the context of osteoporosis, AI can be used to analyze medical images, predict fracture risk, and even recommend personalized treatment plans.

Taiwan has been at the forefront of AI-driven healthcare innovation, with a particular focus on medical imaging and diagnostics. Taiwanese companies and research institutions have developed cutting-edge AI algorithms that can analyze X-rays, CT scans, and other medical images to detect early signs of osteoporosis and assess bone health. These AI tools have the potential to revolutionize osteoporosis screening by making it faster, more accurate, and more widely available.

### Indonesia’s Approval of Taiwanese AI Technology

In a move that underscores Indonesia’s commitment to leveraging advanced technology for public health, the country’s Ministry of Health has officially approved the use of Taiwanese AI technology for osteoporosis screening. This approval follows a rigorous evaluation process, during which the AI technology was tested for its accuracy, reliability, and safety in a clinical setting.

The Taiwanese AI system approved by Indonesia is designed to analyze standard X-ray images to assess bone density and identify early signs of osteoporosis. Unlike traditional BMD tests, which require specialized equipment, this AI-based solution can be integrated into existing medical imaging infrastructure, making it more accessible to healthcare providers across the country. This is particularly important in rural and underserved areas, where access to advanced diagnostic tools is often limited.

### Benefits of AI-Powered Osteoporosis Screening

The adoption of AI technology for osteoporosis screening in Indonesia offers several key benefits:

1. **Early Detection**: AI can detect subtle changes in bone density that may not be visible to the human eye, allowing for earlier diagnosis of osteoporosis. Early detection is critical for preventing fractures and improving long-term outcomes for patients.

2. **Increased Accessibility**: By utilizing standard X-ray images, the AI system can be deployed in a wide range of healthcare settings, including clinics and hospitals that may not have access to specialized BMD testing equipment. This makes osteoporosis screening more accessible to a larger portion of the population.

3. **Cost-Effectiveness**: AI-powered screening is more cost-effective than traditional BMD tests, as it eliminates the need for expensive equipment and reduces the time required for analysis. This can help lower healthcare costs and make osteoporosis screening more affordable for patients.

4. **Improved Accuracy**: AI algorithms have been shown to be highly accurate in detecting osteoporosis and assessing fracture risk. By providing clinicians with precise and reliable data, AI can help improve the quality of care and reduce the risk of misdiagnosis.

5. **Personalized Treatment**: In addition to screening, AI can be used to develop personalized treatment plans based on a patient’s individual risk factors, such as age, gender, and medical history. This can lead to more targeted interventions and better outcomes for patients.

### Implications for the Future of Healthcare in Indonesia

The approval of Taiwanese AI technology for osteoporosis screening is a significant step forward for Indonesia’s healthcare system. It reflects the country’s growing recognition of the potential of AI to address pressing public health challenges and improve the quality of care for its citizens. As Indonesia continues to modernize its healthcare infrastructure, the integration of AI and other advanced technologies will play an increasingly important role in enhancing diagnostic capabilities, improving patient outcomes, and reducing healthcare costs.

Moreover, this development highlights the importance of international collaboration in the field of healthcare innovation. By partnering with Taiwan, a global leader in

**Australian Researchers Utilize Virtual Reality to Support Indigenous Trauma Healing**

In recent years, virtual reality (VR) technology has emerged as a powerful tool in various fields, from education and entertainment to healthcare and therapy. Now, Australian researchers are exploring how VR can be used to support Indigenous communities in healing from trauma, particularly the intergenerational trauma caused by colonization, displacement, and cultural disruption. This innovative approach seeks to combine cutting-edge technology with traditional Indigenous knowledge and practices, offering a new pathway for emotional and psychological healing.

### The Context of Indigenous Trauma in Australia

Indigenous Australians, including Aboriginal and Torres Strait Islander peoples, have endured centuries of trauma stemming from colonization, forced removal from their lands, the Stolen Generations, and systemic discrimination. These experiences have left deep scars, not only on individuals but also on entire communities. Intergenerational trauma, where the effects of trauma are passed down from one generation to the next, is a significant issue, leading to higher rates of mental health challenges, substance abuse, and social disadvantage among Indigenous populations.

While many Indigenous Australians have shown remarkable resilience, the need for culturally sensitive and effective healing strategies remains urgent. Traditional healing practices, including storytelling, connection to land, and spiritual ceremonies, have long played a central role in Indigenous cultures. However, researchers are now exploring how modern technology, such as VR, can complement these practices and provide new avenues for healing.

### Virtual Reality as a Tool for Healing

Virtual reality has the unique ability to create immersive, interactive environments that can evoke powerful emotional responses. In therapeutic settings, VR has been used to treat conditions such as post-traumatic stress disorder (PTSD), anxiety, and phobias by allowing individuals to confront and process their emotions in a controlled and safe environment. Australian researchers are now adapting this technology to address the specific needs of Indigenous communities.

One of the key advantages of VR is its ability to transport users to virtual worlds that can simulate real-life experiences or create entirely new environments. For Indigenous Australians, this can mean reconnecting with traditional lands, cultural practices, and stories, even if physical access to these places is limited. By immersing individuals in virtual representations of their ancestral lands, researchers hope to foster a sense of belonging, identity, and cultural continuity, which are essential components of healing from trauma.

### Collaborative and Culturally Sensitive Approaches

A critical aspect of this research is ensuring that VR interventions are developed in collaboration with Indigenous communities. Researchers are working closely with Indigenous elders, healers, and cultural leaders to ensure that the virtual environments and experiences are culturally appropriate and respectful. This collaborative approach ensures that the technology is not imposed from the outside but is instead shaped by Indigenous knowledge systems and worldviews.

For example, some VR projects involve the creation of virtual landscapes that reflect the natural environments of specific Indigenous groups, complete with traditional flora, fauna, and sacred sites. These virtual environments can be used in therapeutic settings to help individuals reconnect with their cultural heritage and foster a sense of spiritual healing. In other cases, VR is being used to recreate traditional ceremonies or storytelling sessions, allowing younger generations to engage with their culture in a modern and accessible way.

### Addressing Intergenerational Trauma

One of the most promising aspects of VR therapy is its potential to address intergenerational trauma. By creating immersive experiences that allow individuals to engage with their cultural history and identity, VR can help break the cycle of trauma transmission. For younger Indigenous Australians, who may feel disconnected from their cultural roots due to urbanization or the effects of colonization, VR offers a way to reconnect with their heritage in a meaningful and engaging way.

In addition to individual healing, VR can also be used to facilitate group healing sessions, where community members come together in a shared virtual space to participate in cultural practices or ceremonies. This collective approach to healing is deeply rooted in Indigenous traditions, where community and kinship are central to well-being. By leveraging VR technology, researchers hope to create spaces where individuals can heal not only as individuals but as part of a larger community.

### Challenges and Ethical Considerations

While the potential of VR to support Indigenous trauma healing is exciting, there are also challenges and ethical considerations that must be addressed. One concern is ensuring that the technology is accessible to Indigenous communities, particularly those in remote or underserved areas. Researchers are working to develop low-cost and portable VR systems that can be used in a variety of settings, from urban clinics to remote community centers.

Another important consideration is the need to protect Indigenous knowledge and cultural practices. Researchers must ensure that the virtual environments and experiences they create are respectful of Indigenous intellectual property and that the communities retain control over how their culture is represented and shared. This requires ongoing dialogue and collaboration with Indigenous leaders and knowledge holders.

Finally, there is the question of how VR therapy fits within the broader context of Indigenous healing practices. While VR can offer new tools for healing, it is not a replacement for traditional practices. Instead, researchers emphasize that VR should be

**Zesty Lemon and Coconut Cream Sauce: A Burst of Flavor for Your Culinary Creations**

In the world of culinary delights, sauces play a pivotal role in transforming a dish from ordinary to extraordinary. One such versatile and flavorful sauce that has been gaining popularity is the **Zesty Lemon and Coconut Cream Sauce**. This delightful combination of tangy lemon and rich coconut cream offers a unique balance of flavors that can elevate a wide variety of dishes, from seafood to pasta, and even vegetables. In this article, we’ll explore the ingredients, preparation, and various ways to use this sauce in your cooking.

### The Perfect Harmony of Flavors

The beauty of the Zesty Lemon and Coconut Cream Sauce lies in its harmonious blend of contrasting flavors. The bright, citrusy zing of lemon cuts through the creamy richness of coconut, creating a sauce that is both refreshing and indulgent. The result is a sauce that is light yet satisfying, making it an excellent accompaniment to a wide range of dishes.

#### Key Ingredients

1. **Lemon**: The star of the show, lemon provides the zesty, tangy flavor that defines this sauce. Both the juice and zest of the lemon are used to maximize its citrusy punch. Lemon is also rich in vitamin C, making this sauce not only delicious but also nutritious.

2. **Coconut Cream**: Coconut cream is the thick, rich layer that rises to the top of coconut milk. It adds a luscious, velvety texture to the sauce, along with a subtle sweetness that balances the tartness of the lemon. Coconut cream is also a great dairy-free alternative, making this sauce suitable for those who are lactose intolerant or following a vegan diet.

3. **Garlic**: A small amount of garlic adds depth and a savory undertone to the sauce, complementing the lemon and coconut without overpowering them.

4. **Olive Oil**: A drizzle of olive oil helps to sauté the garlic and adds a touch of richness to the sauce.

5. **Herbs**: Fresh herbs such as parsley, cilantro, or basil can be added to enhance the flavor profile of the sauce. These herbs provide a fresh, aromatic element that pairs beautifully with the citrus and coconut.

6. **Salt and Pepper**: To taste, these basic seasonings help to bring out the flavors of the other ingredients.

### How to Make Zesty Lemon and Coconut Cream Sauce

This sauce is incredibly easy to prepare, making it a great option for both weeknight dinners and special occasions. Here’s a simple recipe to get you started:

#### Ingredients:
– 1 cup coconut cream
– 2 tablespoons fresh lemon juice
– 1 teaspoon lemon zest
– 2 cloves garlic, minced
– 1 tablespoon olive oil
– Salt and pepper to taste
– Fresh herbs (optional)

#### Instructions:

1. **Sauté the Garlic**: In a medium-sized saucepan, heat the olive oil over medium heat. Add the minced garlic and sauté for 1-2 minutes, until fragrant and lightly golden. Be careful not to burn the garlic, as it can become bitter.

2. **Add Coconut Cream**: Pour in the coconut cream and stir well to combine with the garlic. Allow the mixture to simmer gently for 2-3 minutes, stirring occasionally.

3. **Incorporate Lemon**: Add the fresh lemon juice and lemon zest to the saucepan. Stir to combine, and let the sauce simmer for another 2-3 minutes. The lemon juice will add brightness, while the zest will intensify the citrus flavor.

4. **Season**: Season the sauce with salt and pepper to taste. If desired, add chopped fresh herbs for an extra layer of flavor.

5. **Serve**: Once the sauce has thickened slightly and the flavors have melded together, remove it from the heat. Serve immediately, or store in an airtight container in the refrigerator for up to 3 days.

### Culinary Uses for Zesty Lemon and Coconut Cream Sauce

One of the best things about this sauce is its versatility. Here are some delicious ways to incorporate it into your meals:

#### 1. **Seafood Dishes**
The zesty lemon and coconut cream sauce pairs beautifully with seafood, particularly fish and shrimp. Try drizzling it over grilled salmon, seared scallops, or shrimp skewers for a tropical twist. The acidity of the lemon cuts through the richness of the seafood, while the coconut cream adds a luxurious finish.

#### 2. **Pasta**
For a light and creamy pasta dish, toss your favorite pasta with this sauce. You can add sautéed vegetables, such as spinach, cherry tomatoes, or mushrooms, for extra texture and flavor. The sauce clings to the pasta beautifully, creating a satisfying yet refreshing meal.

#### 3. **Vegetable Stir-Fries**
This sauce is a fantastic addition to vegetable stir-fries. Whether you’re

**PursueCare Announces Overhaul of Pear Therapeutics’ reSET and reSET-O Digital Therapeutics**

In a significant development within the digital health and addiction treatment space, PursueCare, a leading provider of virtual addiction treatment services, has announced a major overhaul of Pear Therapeutics’ reSET and reSET-O digital therapeutics. This move marks a critical step forward in the integration of technology-driven solutions for substance use disorder (SUD) and opioid use disorder (OUD) treatment, promising enhanced accessibility, improved patient outcomes, and a more seamless user experience.

### Background: Pear Therapeutics and Digital Therapeutics for Addiction

Pear Therapeutics, a pioneer in the field of prescription digital therapeutics (PDTs), developed reSET and reSET-O as FDA-authorized mobile applications designed to treat substance use disorders. These digital therapeutics are intended to complement traditional outpatient treatment programs by providing cognitive behavioral therapy (CBT) and contingency management to patients with SUD and OUD, respectively.

– **reSET** is designed for patients with alcohol, cannabis, cocaine, and stimulant use disorders, offering a 12-week program that helps patients stay engaged in their treatment.
– **reSET-O** is tailored for patients with opioid use disorder and is used in conjunction with medication-assisted treatment (MAT), such as buprenorphine or methadone, to support recovery over a 12-week period.

Both tools have been lauded for their innovative approach to addiction treatment, offering patients a convenient, evidence-based method of engaging with therapy through their smartphones. However, as with any digital health solution, there is always room for improvement in terms of user experience, accessibility, and integration with broader healthcare systems.

### PursueCare’s Overhaul: What’s Changing?

PursueCare’s decision to overhaul reSET and reSET-O reflects the company’s commitment to enhancing the delivery of addiction treatment through virtual care. The overhaul will focus on several key areas:

1. **Improved User Interface and Experience**: One of the primary goals of the overhaul is to make the digital therapeutics more user-friendly. Patients using reSET and reSET-O will benefit from a more intuitive interface, making it easier to navigate the app, access therapy modules, and track progress. This is especially important for individuals who may not be tech-savvy or who are dealing with the cognitive challenges associated with addiction recovery.

2. **Enhanced Integration with PursueCare’s Virtual Treatment Platform**: PursueCare offers a comprehensive virtual addiction treatment platform that includes telemedicine consultations, medication-assisted treatment (MAT), counseling, and care coordination. The overhaul will ensure that reSET and reSET-O are fully integrated with PursueCare’s platform, allowing for seamless communication between patients, clinicians, and care teams. This integration will enable real-time data sharing, allowing clinicians to monitor patient progress and adjust treatment plans as needed.

3. **Expanded Access and Reach**: PursueCare’s virtual care model allows patients to receive treatment from the comfort of their homes, regardless of geographic location. By integrating reSET and reSET-O into its platform, PursueCare aims to expand access to these digital therapeutics, particularly in underserved areas where access to in-person addiction treatment services may be limited. This is a critical step in addressing the treatment gap for individuals struggling with SUD and OUD in rural or remote areas.

4. **Data-Driven Personalization**: The overhaul will also focus on leveraging data analytics to personalize the treatment experience for each patient. By analyzing patient engagement patterns, treatment adherence, and outcomes, PursueCare can tailor the content and pacing of the digital therapeutics to better meet the needs of individual patients. This personalized approach has the potential to improve patient retention and long-term recovery outcomes.

5. **Integration with Medication-Assisted Treatment (MAT)**: For patients using reSET-O in conjunction with MAT, the overhaul will enhance the coordination between digital therapy and medication management. PursueCare’s clinicians will be able to monitor patients’ adherence to MAT, track their progress in the digital therapeutic program, and make data-driven decisions about their treatment plan. This integrated approach is expected to improve outcomes for patients with opioid use disorder, who often require a combination of behavioral therapy and medication to achieve sustained recovery.

### The Importance of Digital Therapeutics in Addiction Treatment

The integration of digital therapeutics into addiction treatment represents a paradigm shift in how care is delivered. Traditional in-person treatment models, while effective, often face barriers such as limited access to care, stigma, and logistical challenges like transportation. Digital therapeutics, on the other hand, offer several advantages:

– **Accessibility**: Patients can access treatment anytime, anywhere, using their smartphones or tablets. This is particularly beneficial for individuals living in rural areas or those with mobility issues.
– **Scalability**: Digital therapeutics can be scaled to reach large populations, addressing the growing demand for addiction treatment services.
– **Eng

**Garlic Sautéed Kale Recipe: A Nutritious and Flavorful Side Dish**

Kale, a leafy green vegetable packed with nutrients, has become a popular ingredient in kitchens around the world. Whether you’re looking to boost your intake of vitamins or simply enjoy a delicious side dish, garlic sautéed kale is a quick, easy, and flavorful option. This recipe combines the earthy taste of kale with the aromatic richness of garlic, resulting in a dish that complements a variety of meals. In this article, we’ll explore the benefits of kale, provide a step-by-step guide to making garlic sautéed kale, and offer tips for customizing the recipe to suit your taste.

### Why Kale?

Kale is a member of the cruciferous vegetable family, which also includes broccoli, cauliflower, and Brussels sprouts. It is celebrated for its impressive nutritional profile, being rich in vitamins A, C, and K, as well as minerals like calcium, potassium, and magnesium. Kale is also a good source of fiber and antioxidants, which help support overall health and may reduce the risk of chronic diseases.

In addition to its nutritional benefits, kale has a hearty texture that holds up well when cooked, making it an ideal vegetable for sautéing. When paired with garlic, it takes on a savory, slightly sweet flavor that enhances its natural taste.

### Ingredients

To make garlic sautéed kale, you’ll need the following ingredients:

– **1 large bunch of kale** (about 8-10 cups, stems removed, leaves roughly chopped)
– **2-3 cloves of garlic**, minced (adjust to taste)
– **2 tablespoons of olive oil** (or your preferred cooking oil)
– **Salt and pepper**, to taste
– **1 tablespoon of lemon juice** (optional, for a bright finish)
– **Red pepper flakes** (optional, for a bit of heat)

### Step-by-Step Instructions

#### 1. **Prepare the Kale**
Start by washing the kale thoroughly to remove any dirt or grit. After washing, remove the tough stems by either tearing or cutting the leaves away. Roughly chop the kale into bite-sized pieces. If you prefer a more tender texture, you can massage the kale for a minute or two with a little olive oil before cooking, which helps break down some of the fibers.

#### 2. **Heat the Oil**
In a large skillet or sauté pan, heat the olive oil over medium heat. Once the oil is hot but not smoking, add the minced garlic. Sauté the garlic for about 30 seconds to 1 minute, stirring constantly to avoid burning. You want the garlic to become fragrant and lightly golden.

#### 3. **Add the Kale**
Once the garlic is fragrant, add the chopped kale to the pan. It may seem like a lot of kale at first, but it will wilt down significantly as it cooks. Stir the kale to coat it evenly with the garlic and oil.

#### 4. **Sauté the Kale**
Continue to sauté the kale for about 5-7 minutes, stirring occasionally. The kale should become tender but still have a slight bite to it. If the pan becomes too dry, you can add a tablespoon or two of water or vegetable broth to help steam the kale and prevent it from sticking.

#### 5. **Season and Finish**
Once the kale is cooked to your desired tenderness, season it with salt and pepper to taste. If you like, you can also add a squeeze of fresh lemon juice for a bright, tangy finish. For those who enjoy a bit of heat, sprinkle in some red pepper flakes.

#### 6. **Serve**
Your garlic sautéed kale is now ready to serve! It makes a wonderful side dish for grilled meats, roasted vegetables, or grain-based dishes like quinoa or rice. You can also use it as a topping for pasta, pizza, or even as a filling for wraps and sandwiches.

### Customization Tips

One of the best things about this recipe is its versatility. Here are a few ideas for customizing your garlic sautéed kale:

– **Add Protein**: For a more substantial dish, you can add cooked chickpeas, white beans, or sautéed tofu to the kale. This turns the side dish into a light, nutritious meal.

– **Incorporate Other Vegetables**: Feel free to mix in other vegetables like onions, bell peppers, or mushrooms. Sauté them along with the garlic before adding the kale for extra texture and flavor.

– **Use Different Greens**: If kale isn’t your favorite, you can substitute it with other leafy greens like spinach, Swiss chard, or collard greens. Just keep in mind that cooking times may vary depending on the type of green you use.

– **Add Nuts or Seeds**: For added crunch and healthy fats, sprinkle some toasted nuts (like almonds or pine nuts) or seeds (like sunflower or pumpkin seeds) over the finished dish

# An All-Inclusive Guide to Preparing Chicken Wings in an Air Fryer

Chicken wings are a popular snack and meal choice, celebrated for their crunchy skin and tender meat. While deep-frying has long been the preferred method for achieving that ideal crispiness, air fryers allow you to savor tasty chicken wings with considerably less oil and fewer calories. This all-inclusive guide will cover everything you need to know about preparing chicken wings in an air fryer, from getting ready to cooking techniques and flavor options.

## Why Opt for an Air Fryer?

Air fryers utilize circulating hot air to prepare food, replicating the effects of deep frying without the excess grease. Here are some advantages of cooking chicken wings in an air fryer:

1. **Healthier Alternative**: Air frying cuts down on the oil required, leading to a lower fat content.
2. **Crispy Finish**: The air fryer provides a crunchy outer layer while keeping the flesh juicy and tender.
3. **Rapid Cooking**: Typically, air fryers cook food quicker than conventional ovens.
4. **Simplicity in Cleanup**: Most air fryer parts are suitable for the dishwasher, making post-cooking cleanup a breeze.

## Selecting the Ideal Chicken Wings

When it comes to chicken wings, you have several choices:

– **Whole Wings**: These comprise three sections: the drumette, flat, and tip. They are perfect for parties and gatherings.
– **Party Wings**: These are pre-portion wings, generally consisting solely of drumettes and flats, making them easy to serve.
– **Fresh vs. Frozen**: Fresh wings provide the best flavor and texture, but frozen wings can be used straight from the freezer with adjusted cooking times.

## Preparation Steps

### 1. Thawing (if using frozen wings)
If using frozen chicken wings, it’s recommended to thaw them in the refrigerator overnight. If time is scarce, the cold water method can be employed: place the wings in a sealed plastic bag and immerse in cold water for roughly 30 minutes.

### 2. Pat Dry
After thawing, dry the wings thoroughly with paper towels. Removing excess moisture is key to getting crispy skin.

### 3. Seasoning
You can keep it straightforward with salt and pepper or experiment with various marinades and dry rubs. Consider these popular choices:

– **Classic Buffalo**: Mix melted butter with hot sauce (such as Frank’s RedHot).
– **Garlic Parmesan**: Combine grated Parmesan cheese, garlic powder, and Italian seasoning.
– **Honey BBQ**: Whisk together honey, BBQ sauce, and a dash of apple cider vinegar.
– **Spicy Asian**: Blend soy sauce, sesame oil, garlic, and a hint of sriracha.

### 4. Marinate (Optional)
For a more robust flavor, let the wings marinate for at least 30 minutes or up to overnight in the refrigerator.

## Cooking Chicken Wings in an Air Fryer

### 1. Preheat the Air Fryer
Set your air fryer to 360°F (182°C). Preheating is essential for uniform cooking and achieving crispy skin.

### 2. Arrange the Wings
Lay the wings out in a single layer within the air fryer basket. Avoid overcrowding to facilitate proper air circulation. You may need to cook in batches based on your air fryer’s size.

### 3. Cooking Time
Cook the wings for approximately 25-30 minutes, flipping them halfway through to ensure even cooking. The internal temperature must reach 165°F (74°C) for safety.

### 4. Crisping (Optional)
For enhanced crispiness, raise the temperature to 400°F (204°C) during the last 5 minutes of cooking.

### 5. Toss in Sauce
If you’re using a sauce, toss the cooked wings in it right after taking them out of the air fryer. This helps the sauce stick better.

## Serving Suggestions

Chicken wings can be enjoyed as an appetizer or a main course. Pair them with:

– **Dipping Sauces**: Ranch, blue cheese, or a spicy aioli.
– **Sides**: Celery and carrot sticks, coleslaw, or potato wedges.
– **Beverages**: Beer, soda, or a refreshing cocktail.

## Tips for Perfect Air Fryer Chicken Wings

– **Utilize Baking Powder**: For added crispness, coat the wings in a mix of baking powder and salt before cooking. This aids in drying out the skin.
– **Check for Doneness**: Always use a meat thermometer to confirm that the wings are adequately cooked.
– **Explore Flavor Combinations**: Feel free to test out different marinades and seasonings to discover your favorite mix.

## Conclusion

Preparing chicken wings in an air fryer is a straightforward and satisfying endeavor that yields delectable results. With the proper preparation, seasoning, and cooking methods, you can relish crispy, flavorful wings without the

**Parakeet Health Secures $3M in Funding for Expansion and Product Development**

*October 2023*

Parakeet Health, a rapidly growing digital health startup, has successfully raised $3 million in a new funding round aimed at accelerating its expansion and product development efforts. The company, known for its innovative approach to personalized healthcare solutions, has garnered attention for its unique platform that leverages artificial intelligence (AI) and data analytics to provide tailored health insights and proactive care management for users.

### A Vision for Personalized Healthcare

Founded in 2020, Parakeet Health was built on the premise that healthcare should be more proactive, accessible, and personalized. The company’s platform integrates data from wearable devices, electronic health records (EHR), and user-reported information to create a comprehensive health profile for each individual. By using AI-driven algorithms, Parakeet Health offers personalized recommendations, tracks health trends, and alerts users to potential health risks before they become critical.

The platform is designed to empower users to take control of their health by providing real-time insights and actionable recommendations. Whether it’s monitoring chronic conditions, managing fitness goals, or keeping track of mental health, Parakeet Health aims to be a one-stop solution for holistic health management.

### The $3M Funding Round

The recent $3 million funding round was led by prominent venture capital firms specializing in healthcare technology, with participation from angel investors and strategic partners in the health and wellness industry. This infusion of capital will be instrumental in scaling Parakeet Health’s operations, expanding its user base, and enhancing its product offerings.

“We’re thrilled to have the support of our investors as we continue to grow and innovate,” said Sarah Mitchell, CEO and co-founder of Parakeet Health. “This funding will allow us to accelerate our product development, expand our team, and bring our vision of personalized healthcare to more people across the globe.”

### Expansion Plans

With the new funding, Parakeet Health plans to expand its reach both geographically and demographically. Currently, the platform is available in the United States, with plans to enter international markets in the coming year. The company is also looking to broaden its user base by targeting specific populations, such as seniors, individuals with chronic illnesses, and fitness enthusiasts.

To support its expansion, Parakeet Health intends to increase its workforce, particularly in the areas of software development, data science, and customer support. The company is also exploring partnerships with healthcare providers, insurance companies, and employers to integrate its platform into existing healthcare ecosystems.

### Product Development and New Features

A significant portion of the $3 million will be allocated to product development, with a focus on enhancing the platform’s AI capabilities and expanding its range of health monitoring features. Parakeet Health is working on integrating more advanced predictive analytics, which will allow users to receive even more accurate and timely health insights.

One of the key areas of development is the addition of mental health monitoring tools. Recognizing the growing importance of mental well-being, Parakeet Health is developing features that will help users track mood, stress levels, and sleep patterns. These insights will be combined with physical health data to provide a more comprehensive view of overall well-being.

Additionally, the company is exploring the integration of telemedicine services, allowing users to connect with healthcare professionals directly through the platform. This would enable users to receive medical advice, prescriptions, and follow-up care without leaving the app, further enhancing the convenience and accessibility of the platform.

### The Growing Demand for Digital Health Solutions

Parakeet Health’s success comes at a time when the demand for digital health solutions is on the rise. The COVID-19 pandemic accelerated the adoption of telehealth and remote monitoring technologies, and many consumers have grown accustomed to managing their health through digital platforms. According to a report by McKinsey, the global digital health market is expected to reach $660 billion by 2025, driven by advancements in AI, wearable devices, and personalized medicine.

Parakeet Health is well-positioned to capitalize on this trend, offering a solution that not only meets the current demand for remote health management but also anticipates the future of personalized, data-driven healthcare.

### Challenges and Opportunities

While Parakeet Health is poised for growth, the company faces several challenges as it scales. The healthcare industry is highly regulated, and navigating the complexities of data privacy, security, and compliance will be critical to the company’s success. Ensuring that the platform adheres to HIPAA (Health Insurance Portability and Accountability Act) standards and other international regulations will be a top priority as the company expands into new markets.

Additionally, the competitive landscape for digital health platforms is becoming increasingly crowded, with established players like Apple Health, Fitbit, and other health tech startups vying for market share. Parakeet Health will need to differentiate itself by continuing to innovate and provide unique value to its users.

However, the company’s focus on personalized healthcare and its commitment to using cutting